Complement the skills and resources of laboratories to develop and accelerate therapeutic innovation projects.
Provide mRNA technologies expertise to academic and private laboratories.
Set up training courses on the technologies.
Developp the relevant tools to obtain scientific knowledge through biomedical and industrial applications.
Foster the emergence of a multidisciplinary community of researchers to promote projects exploiting mRNA in Biotherapy.
1. DNA plasmid models
2. Polymerase
3. Nuclease inhibitors
4. Cofactors
5. Cap analogs
6. Modified nucleosides
In vitro
enzymatic
reaction
Multistep Purification
LiCL,Centrifugation,
diafiltration, ultrafiltation,
chromatography
Capped, polyA and chemically modified mRNA
1. DNA plasmid models
2. Engineered yeast cell
Growth and induction
Integrated Extraction Purification Process
Capped, polyA and naturally modified mRNA
1. DNA plasmid models
2. Polymerase
3. Nuclease inhibitors
4. Cofactors
5. Cap analogs
6. Modified nucleosides
In vitro
enzymatic
reaction
Multistep Purification
LiCL,Centrifugation,
diafiltration, ultrafiltation,
chromatography
Capped, polyA and chemically modified mRNA
1. DNA plasmid models
2. Engineered yeast cell
Growth and induction
Integrated Extraction Purification Process
Capped, polyA and naturally modified mRNA
